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Chemical Intermediates List

 

NO. Product Name Structure Status
101 Carbamazepine intermediates 卡马西平中间体
101-1

Iminodibenzyl
亚氨基二苄
CAS: 494-19-9

Commercial
101-2 Iminostilbene Carbonyl Chloride
亚氨基芪甲酰氯
CAS:33948-22-0
Commercial
102 Carbamazepine Bromine Free intermediates  无溴卡马西平中间体
102-1 Iminostilbene
亚氨基芪
CAS:256-96-2
Commercial
103 Oxcarbazepine intermediates 奥卡西平中间体
103-1 10-Methoxy Iminostilbene
10- 甲氧基亚氨基芪
CAS:4698-11-7
Commercial
104 Paroxetine intermediates  帕罗西汀中间体
104-1 (3S,4R)-3-(3,4-Methylene-dioxyphenoxy-methyl)-4-
(4’-fluorophenyl)-N-methylpiperidine
N- 甲基帕罗西汀
CAS:110429-36-2
Commercial
105 Venlafaxine intermediates 文拉法辛中间体
105-1 1-(4-Methoxyphenyl)-2-Aminoethyl
Cyclohexanol Hydrochloride
1-(4- 甲氧基苯基)-2-胺基乙基环己醇盐酸盐
CAS:130198-05-9
Commercial
201 Ketoprofen intermediates 酮基布洛芬中间体
201-1  2-(3-Benzoylphenyl)Propionitrile
间丙腈基二苯酮
CAS:42872-30-0
Commercial
301 Gliclazide intermediates  格列齐特中间体
301-1 N-Amino-Aza-3-Bicyclo[3,3,0]Octane Hydrochloride
N-氨基-氮杂-3-二环[3,3,0]辛烷盐酸盐
CAS:58108-05-7
Commercial
401 Cabapenem intermediates 培南中间体
401-1 (3R,4R)-4-Acetoxy-3-[(R)-1-(tert-butyldimethylsilyloxy)
ethyl]azetidin-2-one AOSA (4-AA)  
4- 乙酰氧基氮杂环丁酮
CAS: 76855-69-1
Commercial
402 Meropenem intermediates  美罗培南中间体
402-1 P-nitrobenzyl(1r,5r,6s)-6-[(1r)-1-hydroxyethyl]-2-[(diphenylphos
phono)oxy]-1-methylcarbapen-2-em-3-carboxylate MAP    
[4R-[4a,5b,6b(R*)]]-3- 二苯基磷酰氧基-6-(1- 羟基 乙
基)-4- 甲基-7-氧代-1-氮杂双环[3.2.0]庚-2-烯-2-羧酸对硝基苄
酯-1b- 甲基碳青霉烯双环母核(杂氮双环磷酸酯)
CAS: 90776-59-3
Commercial
402-2 (R)-4-Nitrobenzyl-2-diazo-4-((2R,3S)-3-((R)-1-hydroxyethyl)-4-o
 xoazetidin-2-yl)-3-oxopentanoate
(3S,4R)-4-[(1R)-1-羟乙基]-3-[(1R)-1- 甲基-3-重氮-3-对硝基苄
基氧羰基-2-氧代 (美罗中间体 F9)
CAS:137391-68-5
Commercial
501 Sitagliptin intermediates  西他列汀中间体
501-1 Boc-(R)-3-Amino-4-(2.4.5-trifluoromethyl) butyrate
Boc-(R)-3-氨基-4-(2,4,5-三氟苯基)丁酸
CAS: 486460-00-8
Commercial
501-2 2,4,5-Trifluorophenylacetic acid
2,4,5-三氟苯乙酸
CAS: 209995-38-0
Commercial
501-3 3-trifluoro methyl-[1,2,4]triazole[4,3-a]
piperazine hydrochloride
3-(三氟甲基)-5,6,7,8- 四氢-[1,2,4]三唑并[4,3-a]吡嗪盐酸盐
CAS: 762240-92-6
Commercial
601 Sulfasalazine intermediates  柳氮磺吡啶中间体
601-1 Sulfapyridine
磺胺吡啶
CAS:144-83-2
Commercial
701 Imatinib intermediates   伊马替尼中间体
701-1 4-[(4-Methylpiperazin-1-yl)methyl]benzoic acid dihydrochloride
4-[(4-甲基哌嗪-1-基)甲基]苯甲酸二盐酸盐
CAS:106261-49-8
Commercial
701-2 N-(5-Amino-2-methylphenyl)-4-(3-pyridyl)-2-pyrimidine-amine  
N-(5-氨基-2-甲基苯基)-4-(3-吡啶基)-2-氨基嘧啶
CAS:152460-10-1
Commercial
801 Relebactam intermediates  瑞莱巴坦中间体  
801-1 (2S,5S)-5-hydroxypiperidine-2-carboxylic acid
(2S,5S)-5-羟基哌啶-2-羧酸
CAS:63088-78-8
Commercial
801-2
tert-butyl 4-((1R,2S,5R)-6-hydroxy-7-oxo-1,6-diazabicyclo[3.2.1]
octane-2-carboxamido) piperidine-1-carboxylate
4-[[[(1R,2S,5R)-6-羟基-7-氧代-1,6-二氮杂双环[3.2.1]辛烷-2-
基]羰基]氨基]-1-哌啶羧酸叔丁酯
CAS:1174020-64-4
Commercial
901 Avibactam intermediates    阿维巴坦中间体
901-1
(2S,5R)-5-((4-methoxybenzyl)oxy )amino)piperidine-2-
carboxamide
CAS
Commercial
901-2

(2S,5R)-6-((4-methoxybenzyl)oxy)-7-oxo-1,6-diazabicyclo

[3.2.1]octane-2-carboxamide
CAS
Commercial
901-3
(1R,2S,5R)-2-(氨基羰基)-7-氧代-1,6-二氮杂双环[3.2.1]辛-6-基
硫酸酯(四丁基铵)盐
CAS: 1192651-80-1
Commercial
 1001 Cilastatin intermediates 西司他丁中间体 

 1001-1

S,Z)-7-chloro-2-(1,2,2-trimethylcyclopropane-1-
carboxamido)hept-2-enoic acid
7-氯-2-[[[(1S)-2,2-二甲基环丙基]羰基]氨基]-2-庚烯酸
CAS:877674-77-6
Commercial

1101      Semaglutide intermediates 司美格鲁肽中间体

1101-1

Fmoc-Glu(OtBu)-Gly-OH  FMC

(S)-2-(2-((((9H--9-)甲氧基)羰基)氨基)-5-(叔丁氧基)-5- 代戊酰胺基)乙酸

司美格鲁肽中间体  (TTA-A20)

CAS:866044-63-5

Commercial

1101-2

Fmoc-Lys(AEEA-AEEA-g-Glu(OtBu)-Oct(OtBu))-OH

司美格鲁肽中间体  (MAT)

CAS:1662688-20-1

Commercial
1101-3

Fmoc-Gly-Arg(Pbf)-OH

司美格鲁肽中间体 (FMC)

CAS:L1048377-78-1

Commercial
1101-4

Boc-His(Trt)-Aib-Glu(OtBu)-Gly-OH

司美格鲁肽中间体 (TTA)

CAS:1890228-73-5

Commercial
1201    Entresto intermediates 诺欣妥中间体
1201-1

tert-butyl (R)-(1-([1,1'-biphenyl]-4-yl)-3-hydroxypropan

-2-yl)carbamate

LCZ696 中间体

CAS:1426129-50-1

Commercial
1201-2

(R,E)-5-([1,1'-biphenyl]-4-yl)-4-((tert-butoxycarbonyl)

amino)-2-methylpent-2-enoic acid

(R,E)-5-([1,1'-联苯]-4-)-4- [(叔丁氧羰基)氨基]-2

- 甲基-2-戊烯酸

CAS:1012341-48-8

Commercial
1201-3

(2R,4S)-5-([1,1'-biphenyl]-4-yl)-4-((tert-butoxycarbonyl) amino)-2-methylpentanoic acid

(2R,4S)-5-(联苯-4-)-4- [(叔丁氧基羰基)氨基]-2- 甲基戊酸 CAS:1012341-50-2

Commercial
1201-4

(2R,4S)-4-Amino-5-(biphenyl-4-yl)-2-methylpentanoic  Acid   Ethyl Ester Hydrochloride

2R,4S-4-氨基-5-(联苯-4-基) -2- 甲基戊酸乙酯盐酸盐 CAS:149690-12-0

Commercial
1201-5

AHU-377 (heMicalciuM salt)

LCZ696 中间体

CAS:1369773-39-6

Commercial

1301       Dapagliflozin intermediates 达格列净中间体

1301-1

(2R,3R,4R,5S,6S)-2-(acetoxymethyl)-6-(4-chloro-3-

(4-ethoxybenzyl)phenyl)tetrahydro-2H-pyran-3,4,5-triyl triacetate (2R,3R,4R,5S,6S)-2-(乙酰氧基甲基)-6-(4--3-(4- 乙氧基苄基)

苯基)四氢-2H-吡喃-3,4,5-三乙酸酯

CAS:461432-25-7

Commercial

1401          Edoxaban intermediates 艾多沙班中间体

1401-1

tert-butyl

((1R,2S,5S)-2-amino-5-(dimethylcarbamoyl)cyclohexyl)carbamate

[(1R,2S,5S)-2-氨基-5- [(二甲基氨基)...;5S)-2-氨基-5- [(二甲基氨

)羰基]环己基]氨基甲酸叔丁酯

CAS: 365998-36-3

Commercial
1401-2

5-methyl-4,5,6,7-tetrahydrothiazolo[5,4-c]pyridine-2-carboxylic acid 艾多沙班中间体

CAS: 720720-96-7

Commercial
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